KuTenk 2000 - BMST293810-Pharmaceutical Statistics Using SAS A Practical Guide

by Alex Dmitrienko, Christy Chuang-Stein and Ralph D'Agostino 

2007 (464 pages)

ISBN:9781590478868

Providing tutorial material and SAS examples, this book introduces a wide range of data analysis problems encountered in drug development and illustrates them using a wealth of case studies from actual pre-clinical experiments and clinical studies.

Pharmaceutical Statistics Using SAS—A Practical Guide

Preface

Chapter 1

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Statistics in Drug Development

Chapter 2

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Modern Classification Methods for Drug Discovery

Chapter 3

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Model Building Techniques in Drug Discovery

Chapter 4

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Statistical Considerations in Analytical Method Validation

Chapter 5

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Some Statistical Considerations in Nonclinical Safety Assessment

Chapter 6

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Nonparametric Methods in Pharmaceutical Statistics

Chapter 7

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Optimal Design of Experiments in Pharmaceutical Applications

Chapter 8

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Analysis of Human Pharmacokinetic Data

Chapter 9

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Allocation in Randomized Clinical Trials

Chapter 10

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Sample-Size Analysis for Traditional Hypothesis Testing: Concepts and Issues

Chapter 11

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Design and Analysis of Dose-Ranging Clinical Studies

Chapter 12

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Analysis of Incomplete Data

Chapter 13

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Reliability and Validity: Assessing the Psychometric Properties of Rating Scales

Chapter 14

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Decision Analysis in Drug Development