Biosensing Using Nanomaterials | by Arben Merkoçi | 2009 | ISBN: 9780470183090. Carbon Nanotube-Based Sensors and Biosensors. SEQUENCING OF DNA USING CNTs. NANOPARTICLE-BASED ELECTROCHEMICAL BIOSENSORS. QUANTUM DOT BIOSENSING. Inductively Coupled Plasma Mass Spectroscopy-Based Biosensing.
Biosensing Using Nanomaterials
by Arben Merkoçi
2009 (499 pages)
ISBN:9780470183090
Introducing novel concepts in the area of bioanalysis based on nanomaterials, this book opens new opportunities for basic research and new tools for real bioanalytical applications.
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Biosensing Using Nanomaterials
Series Preface
Preface
Part I – Carbon Nanotubes
Chapter 1 – Carbon Nanotube—Based Sensors and Biosensors
1.1: INTRODUCTION TO THE STRUCTURE OF CARBON NANOTUBES
1.2: ELECTROANALYSIS USING CNT-MODIFIED ELECTRODES
1.3: ADVANTAGEOUS APPLICATION OF CNTs IN SENSORS: pH SENSING
1.4: CARBON NANOTUBE-BASED BIOSENSORS
1.5: USING CNTs IN BIOSENSOR PRODUCTION FOR MEDICAL DIAGNOSTICS AND ENVIRONMENTAL APPLICATIONS
REFERENCES
Chapter 2 – Isotropic Display of Biomolecules on CNT-Arrayed Nanostructures
2.1: INTRODUCTION: CNT ARRAYS FOR BIOSENSING
2.2: FUNCTIONALIZATION OF CNTs: CONTROLLING DISPLAY THROUGH COVALENT ATTACHMENT
2.3: SELF-ASSEMBLING INTERFACES: ANCHOR-PROBE APPROACH
2.4: MOLECULAR WIRING OF REDOX ENZYMES
2.5: MULTIPLEXING BIOMOLECULES ON NANOSCALE CNT ARRAYS
2.6: CONCLUSIONS
REFERENCES
Chapter 3 – Interaction of DNA with CNTs—Properties and Prospects for Electronic Sequencing
3.1: INTRODUCTION
3.2: STRUCTURAL PROPERTIES OF COMBINED DNA-CNT SYSTEMS
3.3: ELECTRONIC STRUCTURE
3.4: OPTICAL PROPERTIES
3.5: BIOSENSING AND SEQUENCING OF DNA USING CNTs
3.6: SUMMARY
REFERENCES
Part II – Nanoparticles
Chapter 4 – Improved Electrochemistry of Biomolecules Using Nanomaterials
4.1: INTRODUCTION
4.2: CNT-BASED ELECTROCHEMICAL BIOSENSORS
4.3: NANOPARTICLE-BASED ELECTROCHEMICAL BIOSENSORS
4.4: QUANTUM DOT-BASED ELECTROCHEMICAL BIOSENSORS
4.5: CONCLUSIONS AND OUTLOOK
REFERENCES
Chapter 5 – The Metal Nanoparticle Plasmon Band as a Powerful Tool for Chemo- and Biosensing
5.1: INTRODUCTION
5.2: THE SPB: AN OPTICAL PROPERTY OF METAL NPS
5.3: PLASMON BAND VARIATION UPON AGGREGATION OF NANOPARTICLES
5.4: PLASMON BAND VARIATION ON THE ENVIRONMENT OR LIGAND ALTERATION
5.5: METAL NANOPARTICLES AS LABELS
5.6: CONCLUSIONS
REFERENCES
Chapter 6 – Gold Nanoparticles—A Versatile Label for Affinity Electrochemical Biosensors
6.1: INTRODUCTION
6.2: SYNTHESIS OF AuNPs
6.3: CHARACTERIZATION OF AuNPs
6.4: AuNPs AS DETECTING LABELS FOR AFFINITY BIOSENSORS
6.5: CONCLUSIONS
REFERENCES
Chapter 7 – Quantum Dots for the Development of Optical Biosensors Based on Fluorescence
7.1: INTRODUCTION
7.2: QUANTUM DOTs
7.3: BASIC PHOTOPHYSICS AND QUANTUM CONFINEMENT
7.4: QUANTUM DOT SURFACE CHEMISTRY AND BIOCONJUGATION
7.5: BIOANALYTICAL APPLICATIONS OF QUANTUM DOTs AS FLUORESCENT LABELS
7.6: FLUORESCENCE RESONANCE ENERGY TRANSFER AND QUANTUM DOT BIOSENSING
7.7: SUMMARY
REFERENCES
Chapter 8 – Nanoparticle-Based Delivery and Biosensing Systems—An Example
8.1: INTRODUCTION
8.2: FUNCTIONAL COLLOIDAL NANOPARTICLES
8.3: POLYELECTROLYTE CAPSULES AS A FUNCTIONAL CARRIER SYSTEM
8.4: UPTAKE OF CAPSULES BY CELLS
8.5: DELIVERY AND SENSING WITH POLYELECTROLYTE CAPSULES
8.6: CONCLUSIONS
REFERENCES
Chapter 9 – Luminescent Quantum Dot FRET-Based Probes in Cellular and Biological Assays
9.1: INTRODUCTION
9.2: LUMINESCENT QUANTUM DOTS
9.3: FLUORESCENCE RESONANCE ENERGY TRANSFER
9.4: QUANTUM DOT FRET-BASED PROTEASE PROBES
9.5: SUMMARY AND CONCLUSIONS
REFERENCES
Chapter 10 – Quantum Dot—Polymer Bead Composites for Biological Sensing Applications
10.1: INTRODUCTION
10.2: QUANTUM DOT-COMPOSITE CONSTRUCTION
10.3: APPLICATIONS OF QD COMPOSITES
10.4: FUTURE DIRECTIONS
REFERENCES
Chapter 11 – Quantum Dot Applications in Biomolecule Assays
11.1: INTRODUCTION TO QDs AND THEIR APPLICATIONS
11.2: PREPARATION OF QDs FOR CONJUGATION WITH BIOMOLECULES AND CELLS
11.3: SPECIAL OPTOELECTRONIC PROPERTIES IN THE BIOEMPLOYMENT OF QDs
11.4: EMPLOYMENT OF QDs AS BIOSENSING INDICATORS
REFERENCES
Chapter 12 – Nanoparticles and Inductively Coupled Plasma Mass Spectroscopy—Based Biosensing
12.1: ICP-MS AND APPLICATION POSSIBILITIES
12.2: DETECTION OF METAL IONS
12.3: DETECTION OF NANOPARTICLES
12.4: ANALYSIS OF METAL-CONTAINING BIOMOLECULES
12.5: BIOANALYSIS BASED ON LABELING WITH METAL NANOPARTICLES
12.6: CONCLUSIONS
REFERENCES
Part III – Nanostructured Surfaces
Chapter 13 – Integration between Template-Based Nanostructured Surfaces and Biosensors
13.1: INTRODUCTION
13.2: NANOSPHERE LITHOGRAPHY
13.3: NANOELECTRODES ENSEMBLE FOR BIOSENSING DEVICES
13.4: CONCLUDING REMARKS
REFERENCES
Chapter 14 – Nanostructured Affinity Surfaces for MALDI-TOF-MS—Based Protein Profiling and Biomarker Discovery
14.1: PROTEOMICS AND BIOMARKERS
14.2: MALDI IN THEORY AND PRACTICE
14.3: CARBON NANOMATERIALS
14.4: NEAR-INFRARED DIFFUSE REFLECTION SPECTROSCOPY OF CARBON NANOMATERIALS
REFERENCES
Part IV – Nanopores
Chapter 15 – Biosensing with Nanopores
15.1: NANOPOROUS MATERIALS IN SENSING
15.2: NANOCHANNEL AND NANOPORE FABRICATION
15.3: SURFACE MODIFICATION CHEMISTRY
15.4: NONELECTRICAL NANOPOROUS BIOSENSORS
15.5: ELECTRICAL NANOPOROUS BIOSENSORS
15.6: SUMMARY
REFERENCES
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